1 Result for "

parietal brain cortex

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "parietal brain cortex" in MCE Product Catalog:

12
12 Cited Publications
製品番号: HY-15498
CAS 番号: 1289023-67-1
純度:  99.94%
別名: BMS-927711; BHV-3000
Target:  

CGRP Receptor

研究分野:  

Neurological Disease

Rimegepant (BMS-927711; BHV-3000) is an orally bioavailable and blood-brain barrier permeable antagonist of CGRP and AMY1 receptors, with a pIC50 of 8.01 and a Ki of 0.027 nM for human CGRP receptors. Rimegepant antagonizes cAMP production induced by αCGRP, βCGRP and amylin at CGRP and AMY1 receptors in humans, rats and mice, as well as at rat AMY3 receptors. Rimegepant can be used in research related to migraine .
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