Tau-aggregation-IN-4
Tau-aggregation-IN-4 is a Tau-aggregation inhibitor (EC50 = 2.99 μM). Tau-aggregation-IN-4 can be used for the study of neurodegenerative disorders such as Alzheimer’s and Pick’s diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C23H21N5O2
- 分子量:399.45
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Tau-aggregation-IN-4 (Compound 1a) (10-30 μM, 24 h) scavenges tau aggregates at both 10 μM and 30 μM concentrations (EC50 = 2.99 μM) in SH-SY5Y cells, with an average maximum clearance of 62%, and is non-cytotoxic[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
分子量 399.45
-
分子式 C23H21N5O2
-
SMILES
O=C(C1=CNC2=C1C=CC(NC(CCC3(CCC#C)N=N3)=O)=C2)NC4=CC=CC=C4
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)