Turosteride
Based on 1 Customer Validation
Turosteride is a selective 5 alpha-reductase inhibitor, with IC50 values of 55 and 53 nM for human and rat prostatic 5 alpha-reductases, respectively. Turosteride can reduce the prostate and seminal vesicle weights.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.49%
- CAS 番号: 137099-09-3
- 分子式: C27H45N3O3
- 分子量:459.66
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
化学情報
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CAS 番号 137099-09-3
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性状 Solid
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分子量 459.66
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分子式 C27H45N3O3
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@@H]2C(N(C(C)C)C(NC(C)C)=O)=O)([H])[C@@]3([H])[C@]([C@@]4([C@@](N(C(CC4)=O)C)([H])CC3)C)([H])CC1
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別名
FCE 26073
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 50 mg/mL (108.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
純度とドキュメンテーション
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データシート (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1755 mL | 10.8776 mL | 21.7552 mL | 54.3880 mL |
| 5 mM | 0.4351 mL | 2.1755 mL | 4.3510 mL | 10.8776 mL | |
| 10 mM | 0.2176 mL | 1.0878 mL | 2.1755 mL | 5.4388 mL | |
| 15 mM | 0.1450 mL | 0.7252 mL | 1.4503 mL | 3.6259 mL | |
| 20 mM | 0.1088 mL | 0.5439 mL | 1.0878 mL | 2.7194 mL | |
| 25 mM | 0.0870 mL | 0.4351 mL | 0.8702 mL | 2.1755 mL | |
| 30 mM | 0.0725 mL | 0.3626 mL | 0.7252 mL | 1.8129 mL | |
| 40 mM | 0.0544 mL | 0.2719 mL | 0.5439 mL | 1.3597 mL | |
| 50 mM | 0.0435 mL | 0.2176 mL | 0.4351 mL | 1.0878 mL | |
| 60 mM | 0.0363 mL | 0.1813 mL | 0.3626 mL | 0.9065 mL | |
| 80 mM | 0.0272 mL | 0.1360 mL | 0.2719 mL | 0.6799 mL | |
| 100 mM | 0.0218 mL | 0.1088 mL | 0.2176 mL | 0.5439 mL |