1. Metabolic Enzyme/Protease
  2. MAGL
  3. JZP-MA-13

JZP-MA-13 is a selective α/β-hydrolase domain 6 (ABHD6) inhibitor with an IC50 of 392 nM. JZP-MA-13 shows no inhibition of MAGL, ABHD12, FAAH, or other serine hydrolases. JZP-MA-13 is a positron emission tomography (PET) ligand for in vivo imaging of the ABHD6.

For research use only. We do not sell to patients.

JZP-MA-13 Chemical Structure

JZP-MA-13 Chemical Structure

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Description

JZP-MA-13 is a selective α/β-hydrolase domain 6 (ABHD6) inhibitor with an IC50 of 392 nM. JZP-MA-13 shows no inhibition of MAGL, ABHD12, FAAH, or other serine hydrolases. JZP-MA-13 is a positron emission tomography (PET) ligand for in vivo imaging of the ABHD6[1].

IC50 & Target

IC50: 392 nM (ABHD6)[1]

In Vitro

JZP-MA-13 does not bind orthosterically to CB1 or CB2 or allosterically influences canonical CB1 or CB2 signaling[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

338.36

Formula

C14H15FN4O3S

SMILES

FC1=CC=C(C=C1)N(C)C(OC2=NSN=C2N3CCOCC3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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JZP-MA-13 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
JZP-MA-13
Cat. No.:
HY-152152
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