KCNK13-IN-1
KCNK13-IN-1 (example 71), a KCNK13 antagonist, is an anti-inflammatory agent, with an IC50 of <200 nM for IL-1 β.
For research use only. We do not sell to patients.
- CAS No.: 361368-24-3
- Formula: C15H12N6O
- Molecular Weight:292.30
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Chemical Information
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CAS No. 361368-24-3
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Appearance Solid
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Molecular Weight 292.30
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Formula C15H12N6O
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Color White to off-white
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SMILES
NC1=NON=C1C2=NC3=CC=CC=C3N2CC4=CC=NC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 11.3 mg/mL (38.66 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4211 mL | 17.1057 mL | 34.2114 mL | 85.5286 mL |
| 5 mM | 0.6842 mL | 3.4211 mL | 6.8423 mL | 17.1057 mL | |
| 10 mM | 0.3421 mL | 1.7106 mL | 3.4211 mL | 8.5529 mL | |
| 15 mM | 0.2281 mL | 1.1404 mL | 2.2808 mL | 5.7019 mL | |
| 20 mM | 0.1711 mL | 0.8553 mL | 1.7106 mL | 4.2764 mL | |
| 25 mM | 0.1368 mL | 0.6842 mL | 1.3685 mL | 3.4211 mL | |
| 30 mM | 0.1140 mL | 0.5702 mL | 1.1404 mL | 2.8510 mL |