D2343
D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.
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- CAS No.: 72734-63-5
- 화학식: C20H27NO3
- 분자량:329.43
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
제품 설명
IC50 & Target
In Vitro
D2343 is a compound with about the same beta 2-adrenoceptor-agonist effect as Terbutaline and exhibiting in addition an alpha 1-receptor inhibitory activity[1]. The beta 2-agonistic and alpha 1-antagonistic drug D2343 inhibits the evoked contractions in a concentration related fashion with 50% effect at 9.6 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 72734-63-5
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분자량 329.43
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화학식 C20H27NO3
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SMILES
OC(C1=CC=C(O)C=C1)CNC(C)(C)CCC2=C(C=CC=C2)OC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Olsson OA, et al. The effects in myometrial preparations of D2343, a beta 2-adrenoceptor agonist possessing alpha 1-receptor blocking qualities. Acta Pharmacol Toxicol (Copenh). 1984 Nov;55(5):391-7. [Content Brief]
[2]. Olsson OA, et al. The effect of D2343 in transmurally stimulated rabbit isthmus muscle. Acta Pharmacol Toxicol (Copenh). 1985 May;56(5):427-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D2343 Related Classifications
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