D2343
D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.
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- CAS No.: 72734-63-5
- 화학식: C20H27NO3
- 분자량:329.43
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Adrenergic Receptor Isoforms
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Biological Activity
D2343 is a compound with about the same beta 2-adrenoceptor-agonist effect as Terbutaline and exhibiting in addition an alpha 1-receptor inhibitory activity[1]. The beta 2-agonistic and alpha 1-antagonistic drug D2343 inhibits the evoked contractions in a concentration related fashion with 50% effect at 9.6 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 72734-63-5
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분자량 329.43
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화학식 C20H27NO3
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SMILES
OC(C1=CC=C(O)C=C1)CNC(C)(C)CCC2=C(C=CC=C2)OC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Olsson OA, et al. The effects in myometrial preparations of D2343, a beta 2-adrenoceptor agonist possessing alpha 1-receptor blocking qualities. Acta Pharmacol Toxicol (Copenh). 1984 Nov;55(5):391-7. [Content Brief]
[2]. Olsson OA, et al. The effect of D2343 in transmurally stimulated rabbit isthmus muscle. Acta Pharmacol Toxicol (Copenh). 1985 May;56(5):427-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)