country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-126756

Copy Link Print Information

Amorphin

Amorphin is a phosphorylase b with glycogen metabolism activity. Amorphin binds directly to alpha-actinin, with alpha-actinin mediating its binding to actin filaments. Amorphin can be used for the research of McArdle’s disease and breast cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 4207-90-3
화학식: C₃₄H₄₀O₁₆
분자량:704.68

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Amorphin Chemical Structure

CAS No.: 4207-90-3

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Amorphin (Compound 7) (68 h) selectively inhibits the proliferation of MCF-7 human breast cancer cells with an IC₅₀ of 0.95 μM, and has no effect on HCT-116 human colorectal cancer cells at concentrations up to 50 μM^[1].
Amorphin (1 μg/mL; 2 h at 4°C) directly binds to biotinylated alpha-actinin in a solid-phase dot blot assay^[2].
Amorphin (0.31-20 μg/mL; 15 min) binds with higher affinity to purified alpha-actinin than to purified F-actin in a solid-phase radioimmune assay^[2].
Amorphin (0.5 mg/mL; 5 min) binds to actin filaments only when they are decorated with purified alpha-actinin, as observed via negative stain electron microscopy^[2].
Amorphin binds specifically to the Z-bands of extracted glycerinated adult chicken pectoralis muscle myofibrils, restoring their electron-dense amorphous structure^[2].
Amorphin partial peptide sequencing confirms it is nearly identical to rabbit phosphorylase b, demonstrating amorphin is a phosphorylase b^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 4207-90-3
분자량 704.68
화학식 C₃₄H₄₀O₁₆
SMILES

O=C1C=2C(=C3C(O[C@@H](C(CO[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@@H](O)[C@@H](O)CO5)[C@@H](O)[C@H](O)[C@H]4O)=C)C3)=CC2)O[C@]6([C@@]1(C=7C(OC6)=CC(OC)=C(OC)C7)[H])[H]
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Wu X, et al. Cytotoxic rotenoid glycosides from the seeds of Amorpha fruticosa. Fitoterapia. 2015;100:75-80. [Content Brief]

[2]. Chowrashi P, et al. Amorphin is phosphorylase; phosphorylase is an alpha-actinin-binding protein. Cell Motil Cytoskeleton. 2002;53(2):125-135. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기