AR antagonist 7
AR antagonist 7 (86) is an androgen receptor (AR) antagonist that can be used in the research of hair loss.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 876759-97-6
- 화학식: C16H12F3NO2
- 분자량:307.27
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
299 nM
Compound: 6l
|
Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced response
Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced response
|
[PMID: 19286380] |
| Sf9 | IC50 |
69 nM
Compound: 6l
|
Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell system
Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell system
|
[PMID: 19286380] |
Chemical Information
-
CAS No. 876759-97-6
-
분자량 307.27
-
화학식 C16H12F3NO2
-
SMILES
N#CC1=CC=C(OC2=CC=C(C)C=C2OC)C=C1C(F)(F)F
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)