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Cat. No.: HY-105458

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BL-2401

BL-2401 is an orally active enkephalinase inhibitor. BL-2401 exhibit antinociceptive and antidepressant-like activitiesin association with endogenous opioid systems. BL-2401 can be used for the research of neurological disease.

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CAS No.: 151774-56-0
화학식: C₂₁H₂₃NO₄S
분자량:385.48

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BL-2401 Chemical Structure

CAS No.: 151774-56-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

In Vivo

BL-2401 (p.o.) produces an antinociceptive effect in the mouse phenylbenzoquinone writhing test (ED₅₀ = 12.4 mg/kg) and the rat acetic acid writhing test (ED₅₀ = 55.8 mg/kg)^[1].
BL-2401 (100 mg/kg, p.o.) produces a naloxone-reversible antidepressant-like effect in the mouse forced swimming test^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 151774-56-0
분자량 385.48
화학식 C₂₁H₂₃NO₄S
SMILES

CCC(SCC(CC1=CC=CC=C1)C(NC2=CC(C(O)=O)=CC(C)=C2)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kita A, et al. Antinociceptive and antidepressant-like profiles of BL-2401, a novel enkephalinase inhibitor, in mice and rats. Jpn J Pharmacol. 1997 Dec;75(4):337-46. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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