BMS-159
BMS-159 is an orally active, direct phosphate prodrug of BMS-135. BMS-135 is a potent ATP-competitive inhibitor of CK2. BMS-159 can be used in the research of neurological disorders and tumors.
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- CAS No.: 1541248-45-6
- 화학식: C22H24ClN10O6P
- 분자량:590.92
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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CK2 |
Chemical Information
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CAS No. 1541248-45-6
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분자량 590.92
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화학식 C22H24ClN10O6P
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SMILES
N#CC1=CN=C2N1N=C(N=C2NCC)NC3=C(C(N4C[C@H]([C@@H](CC4)NC(OC)=O)OP(O)(O)=O)=CC(C#N)=C3)Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. A M Subbaiah M, et al. Enhancing the Oral Bioavailability of a Poorly Soluble Pan-CK2 Kinase Inhibitor: Leveraging a Phosphate Prodrug Strategy to Overcome Dissolution-Limited Absorption and Improve Systemic Exposure during Dose Escalation. J Med Chem. 2026 Jan 22;69(2):1641-1660. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-159 Related Classifications
HY-180987 Related Classifications
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