DMS-612
DMS-612 (NSC-281612) is an alkylating agent with anti-renal cell carcinoma activity. DMS-612 can be used in cancer research.
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- CAS No.: 56967-08-9
- 화학식: C14H21NO7S2
- 분자량:379.45
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
In Vitro
DMS-612 (1000 ng/mL, 0-24 h) The IC50 values of 786-0, ACHN, SN12K1, AKI-1, and A498 cells are 0.267, 0.263, 0.790, 0.202, 0.0463 μg/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 56967-08-9
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분자량 379.45
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화학식 C14H21NO7S2
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SMILES
O=CC1=CC=C(N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)C=C1C
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Synonyms
NSC-281612
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Parise RA, et al. Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma lines. Cancer Chemother Pharmacol. 2013 Jan;71(1):73-83. doi: 10.1007/s00280-012-1980-1. Epub 2012 Oct 5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)