Ganoderic acid SZ
Ganoderic acid SZ is a natural product with 3-hydroxy-3-methylglutaryl-CoA reductase inhibitory activity. Ganoderic acid SZ shows stronger activity than the positive control atorvastatin in inhibiting HMG-CoA reductase. Ganoderic acid SZ exhibits significant inhibition of yeast-derived α-glucosidase with IC50 values achieved at very low concentrations. Ganoderic acid SZ also exhibits cytotoxicity against K562 cells with IC?? values in the range of 10-20 μM.
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- CAS No.: 865543-37-9
- 화학식: C30H44O3
- 분자량:452.67
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
65.2 μM
Compound: 23
|
Cytotoxicity against human K562 cells by MTT method
Cytotoxicity against human K562 cells by MTT method
|
[PMID: 26287401] |
| PC-3 | IC50 |
75.2 μM
Compound: 23
|
Cytotoxicity against human PC3 cells by MTT method
Cytotoxicity against human PC3 cells by MTT method
|
[PMID: 26287401] |
Chemical Information
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CAS No. 865543-37-9
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분자량 452.67
-
화학식 C30H44O3
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SMILES
C[C@]12C3=CC[C@](C(C)(C(CC4)=O)C)([H])[C@@]4(C)C3=CC[C@@]1([C@@](CC2)([H])[C@H](C)CC/C=C(C)\C(O)=O)C
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Structure Classification
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Initial Source
Ganoderma lucidum
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)