Heclin (Standard)
Heclin (Standard) is the analytical standard of Heclin (HY-110204). This product is intended for research and analytical applications. Heclin is a HECT E3 ubiquitin ligases inhibitor. Heclin inhibits Smurf2, Nedd4, WWP1 (IC50 values are 6.8, 6.3, 6.9 μM) and can be used for the research of gastric cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 890605-54-6
- 화학식: C17H17NO3
- 분자량:283.32
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 890605-54-6
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분자량 283.32
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화학식 C17H17NO3
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SMILES
CC(C(C=C1)=CC=C1NC(/C=C/C2=CC=C(CC)O2)=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Wang K, et al. Targeting the E3 ligase NEDD4 as a novel therapeutic strategy for IGF1 signal pathway-driven gastric cancer [J]. Oncogene, 2023, 42(14): 1072-1087. [Content Brief]
[2]. Su B C, Chen J Y. Antimicrobial peptide epinecidin-1 modulates MyD88 protein levels via the proteasome degradation pathway [J]. Marine Drugs, 2017, 15(11): 362. [Content Brief]
[3]. Mund T, et al. Peptide and small molecule inhibitors of HECT-type ubiquitin ligases [J]. Proceedings of the National Academy of Sciences, 2014, 111(47): 16736-16741. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)