Hepta-histidine
Hepta-histidine is an inhibitor of Ku70-Huntingtin protein interaction. Hepta-histidine can reverse the morphological abnormalities of primary neurons differentiatied from hiPSCs. Hepta-histidine prolongs the lifespan in severe Huntington’s disease R6/2 mouse model. Hepta-histidine ameliorates DNA damage in vitro. Hepta-histidine can be used to study anti-aggregation agent against Tau-associated neurodegenerative diseases such as Alzheimer’s disease and Huntington’s disease.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 64134-31-2
- 화학식: C42H51N21O8
- 분자량:978.01
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocol
- 순도&문서
- References
-
Help & FAQs
Biological Activity
제품 설명
Chemical Information
-
CAS No. 64134-31-2
-
분자량 978.01
-
화학식 C42H51N21O8
-
Sequence
His-His-His-His-His-His-His
-
Sequence Shortening
HHHHHHH
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Kondo K, et al., Hepta-Histidine Inhibits Tau Aggregation. ACS Chem Neurosci. 2021 Aug 18;12(16):3015-3027. [Content Brief]
[2]. Imamura T, et al., Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. Sci Rep. 2016 Sep 22;6:33861. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hepta-histidine Related Classifications
HY-180346 Related Classifications
Powered by Bioz