m-THPP
Based on 1 Customer Validation
m-THPP (Tetra(3-hydroxyphenyl)porphyrin; 3-THPP) is a photosensitizer. m-THPP can weakly induce ROS production and shows antitumor and antibacterial activity. m-THPP can be used for the research of photodynamic therapy (PDT).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 22112-79-4
- 화학식: C44H30N4O4
- 분자량:678.73
-
보관:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
-
Anti-Infection Compound Library
HY-L002
-
Immunology/Inflammation Compound Library
HY-L007
-
Metabolism/Protease Compound Library
HY-L012
-
NF-κB Signaling Compound Library
HY-L014
-
Anti-Cancer Compound Library
HY-L025
-
Anti-Aging Compound Library
HY-L034
-
Antibacterial Compound Library
HY-L049
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
Lactylation Compound Library
HY-L249
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
25.69 nM
Compound: mTHPC
|
Photocytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
Photocytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
|
[PMID: 37634417] |
| MDA-MB-231 | IC50 |
3.31 μM
Compound: mTHPC
|
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
|
[PMID: 37634417] |
| NIH3T3 | IC50 |
12.53 nM
Compound: mTHPC
|
Photocytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
Photocytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability preincubated for 24 hrs followed by washout and 1 J/cm2 light irradiation for 24 hrs by resazurin reduction assay
|
[PMID: 37634417] |
| NIH3T3 | IC50 |
9.16 μM
Compound: mTHPC
|
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability incubated for 24 hrs under dark condition by resazurin reduction assay
|
[PMID: 37634417] |
Chemical Information
-
CAS No. 22112-79-4
-
Appearance Solid
-
분자량 678.73
-
화학식 C44H30N4O4
-
SMILES
OC1=CC=CC(/C2=C3C=CC(/C(C4=CC(O)=CC=C4)=C5C=C/C(N/5)=C(C(C=C/6)=NC6=C(C7=CC=C2N7)\C8=CC(O)=CC=C8)\C9=CC(O)=CC=C9)=N\3)=C1
-
Synonyms
Tetra(3-hydroxyphenyl)porphyrin; 3-THPP
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
순도&문서
-
Data Sheet (276 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
m-THPP Related Classifications
HY-W075248 Related Classifications
Powered by Bioz