MTEP hydrochloride (Standard)
MTEP (hydrochloride) (Standard) is the analytical standard of MTEP (hydrochloride). This product is intended for research and analytical applications. MTEP hydrochloride is a potent, non-competitive and highly selective mGluR5 antagonist, with an IC50 of 5 nM and a Ki of 16 nM. MTEP hydrochloride shows antidepressant and anxiolytic-like effects. MTEP hydrochloride can be used for Parkinson's disease research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98%
- CAS No.: 1186195-60-7
- 화학식: C11H9ClN2S
- 분자량:236.72
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-13206
MTEP hydrochloridemGlu5 Antagonist -
HY-70059
LY341495mGluR Antagonist -
HY-14609A
MPEPmGlu5 Receptor Antagonist -
HY-N0390
L-GlutamineEndogenous Metabolite -
HY-N0390R
L-Glutamine (Standard)Reference Standard -
HY-14609
MPEP HydrochloridemGlu5 Receptor Antagonist -
HY-15446
BasimglurantmGlu5 Negative Allosteric Modulator -
HY-15445
CTEPmGluR Antagonist -
HY-14612
CPPHAmGluR5/mGluR1 Modulator -
HY-15393
VU 0357121mGlu5R Activator -
HY-100403
Ro 67-7476mGluR1 PAM -
HY-14859
DipraglurantmGluR5 NAM
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1186195-60-7
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분자량 236.72
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화학식 C11H9ClN2S
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SMILES
CC1=NC(C#CC2=CC=CN=C2)=CS1.[H]Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Lea PM 4th, et al. Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. CNS Drug Rev. 2006 Summer;12(2):149-66. [Content Brief]
[2]. Ossowska K, et al. MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats. Neuropharmacology. 2005 Sep;49(4):447-55. [Content Brief]
[3]. Pałucha A, et al. Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist. Pharmacol Biochem Behav. 2005 Aug;81(4):901-6. [Content Brief]
[4]. Klodzinska A, et al. Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling. Neuropharmacology. 2004 Sep;47(3):342-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MTEP hydrochloride (Standard) Related Classifications
HY-13206R Related Classifications
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