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Cat. No.: HY-108637R

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PhiKan 083 (Standard)

PhiKan 083 (Standard) is the analytical standard of PhiKan 083 (HY-108637). This product is intended for research and analytical applications. PhiKan 083 is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a K_d of 167 μM. PhiKan 083 can be used for cancer research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 880813-36-5
화학식: C₁₆H₁₈N₂
분자량:238.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

PhiKan 083 (Standard) Chemical Structure

CAS No.: 880813-36-5

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information

Information

신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 880813-36-5
분자량 238.33
화학식 C₁₆H₁₈N₂
SMILES

CNCC1=CC2=C(C=C1)N(CC)C3=C2C=CC=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Boeckler FM, et al. Targeted rescue of a destabilized mutant of p53 by an in silico screened drug. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10360-5. [Content Brief]

[2]. Rauf SM, et al. Effect of Y220C mutation on p53 and its rescue mechanism: a computer chemistry approach. Protein J. 2013 Jan;32(1):68-74. [Content Brief]

[3]. Paulmurugan R, et al. A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblastoma cells. Oncotarget. 2018 Apr 20;9(30):21495-21511. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Product Information
- Information
- 신청
Chemical Information
순도&문서

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

PhiKan 083 (Standard)

PhiKan 083

NSC319726

NSC59984

Pifithrin-β hydrobromide

CP-31398 dihydrochloride

Idasanutlin

Amifostine thiol dihydrochloride

SJ-172550

Pifithrin-α hydrobromide

CBL0137 hydrochloride

Amifostine

CBL0137

Product Information

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Bioz

PhiKan 083 (Standard)

PhiKan 083

NSC319726

NSC59984

Pifithrin-β hydrobromide

CP-31398 dihydrochloride

Idasanutlin

Amifostine thiol dihydrochloride

SJ-172550

Pifithrin-α hydrobromide

CBL0137 hydrochloride

Amifostine

CBL0137

Product Information

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PhiKan 083 (Standard) Related Classifications

HY-108637R Related Classifications

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