country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-111026

Copy Link Print Information

PPQ-581

PPQ-581 is an anti-influenza agent with an EC₅₀ of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 950381-32-5
화학식: C₂₅H₂₄FN₃O₃
분자량:433.47

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

PPQ-581 Chemical Structure

CAS No.: 950381-32-5

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
MDCK	EC₅₀	1 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells after 48 to 72 hrs Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells after 48 to 72 hrs	[PMID: 26310893]
MDCK	EC₅₀	1 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y52H mutant assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y52H mutant assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]
MDCK	EC₅₀	1.4 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y289H mutant assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein Y289H mutant assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]
MDCK	EC₅₀	2.3 μM Compound: 6a	Antiviral activity against wild-type Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against wild-type Influenza A virus (A/WSN/1933(H1N1)) assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]
MDCK	EC₅₀	8 μM Compound: 6a	Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein S377G mutant assessed as virus-mediated cytopathic effect in MDCK cells Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing nucleoprotein S377G mutant assessed as virus-mediated cytopathic effect in MDCK cells	[PMID: 26310893]

Chemical Information

CAS No. 950381-32-5
분자량 433.47
화학식 C₂₅H₂₄FN₃O₃
SMILES

O=C1C2=C(N3C(C(C4=C(F)C=CC=C4)OCC3(C)C)=C2N(C)C(N1C)=O)C5=CC=CC=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lin MI, et al. Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1. Eur J Med Chem. 2015 Sep 18;102:477-86. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기