TLK1
TLK1 is a serine/threonine kinase of the tousled-like kinase (TLK) family, named after the Arabidopsis tousled mutant. It is activated during S phase, and its best-characterized substrates are the histone chaperones ASF1A and ASF1B and the DNA damage regulator Rad9, linking TLK1 to chromatin assembly, DNA replication and checkpoint control. Chk1- and Chk2-mediated phosphorylation inhibits TLK1 after DNA damage, transiently halting chromatin replication. TLK1 also participates in homologous recombination repair, and splice variants of TLK1 have been described in tumors.
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TLK1 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 화학식: Human
- 분자량: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
