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United States

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Cat. No.: HY-158198

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PRXS571

PRXS571 is a potent modulator of the neuronal integrated stress response (ISR) and can be used in neural-related research.

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CAS No.: 2396759-31-0
화학식: C₂₃H₂₃Cl₂FN₄O₃
분자량:493.36

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PRXS571 Chemical Structure

CAS No.: 2396759-31-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PRXS571 is a potent modulator of the neuronal integrated stress response (ISR) and can be used in neural-related research^[1].

IC₅₀ & Target

integrated stress response (ISR)^[1]

Chemical Information

CAS No. 2396759-31-0
분자량 493.36
화학식 C₂₃H₂₃Cl₂FN₄O₃
SMILES

FC(C=C1OC[C@H](O)CN(CC2)CCN2NC(C3=NC4=C(C=C(C=C4)Cl)C=C3)=O)=C(C=C1)Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Marlin E, et al. Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model. Br J Pharmacol. 2024 Feb;181(3):495-508. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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