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Cat. No.: HY-123549

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PSB-6426

PSB-6426 (compund 19a) is a selective human NTPDase2 inhibitor (K_i=8.2 μM). PSB-6426 can be used in stroke and cancer research.

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CAS No.: 958459-33-1
화학식: C₂₂H₂₉N₄O₁₀P
분자량:540.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PSB-6426 Chemical Structure

CAS No.: 958459-33-1

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PSB-6426 (compund 19a) is a selective human NTPDase2 inhibitor (K_i=8.2 μM). PSB-6426 can be used in stroke and cancer research^[1].

IC₅₀ & Target^[1]

NTPDase2

8.2 μM (Ki)

All NTPDase Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	42 μM Compound: 19a, PSB-6426	Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresis Inhibition of human NTPDase 2 expressed in HEK293 cells assessed as residual activity by capillary electrophoresis	[PMID: 18630897]

Chemical Information

CAS No. 958459-33-1
분자량 540.46
화학식 C₂₂H₂₉N₄O₁₀P
SMILES

CCOP(CC(C=C1)=CC=C1NC(CNC([C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(NC(C=C3)=O)=O)O2)=O)=O)(OCC)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Brunschweiger, et al. "Selective nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) inhibitors: nucleotide mimetics derived from uridine-5′-carboxamide." Journal of medicinal chemistry 51.15 (2008): 4518-4528. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
MCE Japan Authorized Agent:

상품명:
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PSB-6426

All NTPDase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PSB-6426 Related Classifications

HY-123549 Related Classifications