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United States

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Cat. No.: HY-123799

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SB-699393

B-699393 (Compound 17) is a BRAF inhibitor (K_d = 7.2 nM) that can cross the blood-brain barrier. SB-699393 can be used for research on stroke.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 502638-39-3
화학식: C₂₃H₂₃N₃O₃
분자량:389.45

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

SB-699393 Chemical Structure

CAS No.: 502638-39-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

B-699393 (Compound 17) is a BRAF inhibitor (K_d = 7.2 nM) that can cross the blood-brain barrier. SB-699393 can be used for research on stroke^[1].

All Raf Isoforms :

Chemical Information

CAS No. 502638-39-3
분자량 389.45
화학식 C₂₃H₂₃N₃O₃
SMILES

O/N=C1C2=CC=C(C3=C(C4=CC=NC=C4)OC(CN5CCOCC5)=C3)C=C2CC/1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Takle AK, et al. The identification of potent, selective and CNS penetrant furan-based inhibitors of B-Raf kinase. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4373-6. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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SB-699393

All Raf Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

SB-699393 Related Classifications

HY-123799 Related Classifications