Seclazone
Based on 1 Customer Validation
Seclazone, a heterocyclic compound, possesses anti-inflammatory, analgesic, antipyretic and diuretic properties. Seclazone is orally active.
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- Purity: 95.0%
- CAS No.: 29050-11-1
- 화학식: C10H8ClNO3
- 분자량:225.63
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Seclazone significantly lowers the fever induced in rats by administration of a yeast suspension[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Charles River rats (150-170 g) [1]
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Dosage:220 mg/kg
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Administration:Oral administration, dietary, daily
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Result:Inhibited adjuvant-induced polyarthritis
Chemical Information
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CAS No. 29050-11-1
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Appearance Solid
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분자량 225.63
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화학식 C10H8ClNO3
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Color Off-white to light yellow
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SMILES
O=C1N(OCC2)C2OC3=CC=C(Cl)C=C13
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 14.29 mg/mL (63.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4320 mL | 22.1602 mL | 44.3203 mL | 110.8009 mL |
| 5 mM | 0.8864 mL | 4.4320 mL | 8.8641 mL | 22.1602 mL | |
| 10 mM | 0.4432 mL | 2.2160 mL | 4.4320 mL | 11.0801 mL | |
| 15 mM | 0.2955 mL | 1.4773 mL | 2.9547 mL | 7.3867 mL | |
| 20 mM | 0.2216 mL | 1.1080 mL | 2.2160 mL | 5.5400 mL | |
| 25 mM | 0.1773 mL | 0.8864 mL | 1.7728 mL | 4.4320 mL | |
| 30 mM | 0.1477 mL | 0.7387 mL | 1.4773 mL | 3.6934 mL | |
| 40 mM | 0.1108 mL | 0.5540 mL | 1.1080 mL | 2.7700 mL | |
| 50 mM | 0.0886 mL | 0.4432 mL | 0.8864 mL | 2.2160 mL | |
| 60 mM | 0.0739 mL | 0.3693 mL | 0.7387 mL | 1.8467 mL |