STING agonist-7
Based on 1 Customer Validation
STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 97.22%
- CAS No.: 2767442-46-4
- 화학식: C17H12N4O4
- 분자량:336.30
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| H69AR | EC50 |
>100 μM
Compound: 11
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Agonist activity at STING in human THP1 Dual cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
Agonist activity at STING in human THP1 Dual cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
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[PMID: 35108011] |
| H69AR | EC50 |
>100 μM
Compound: 11
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Agonist activity at STING in human THP1-Dual cells assessed as NF-kappaB reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
Agonist activity at STING in human THP1-Dual cells assessed as NF-kappaB reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
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[PMID: 35108011] |
Chemical Information
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CAS No. 2767442-46-4
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Appearance Solid
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분자량 336.30
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화학식 C17H12N4O4
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Color Light brown to brown
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SMILES
O=C(C1=CC=CC2=C1OC(CNC(C3=C4N=CC=CN4N=C3)=O)=C2)O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
DMSO : 62.5 mg/mL (185.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9735 mL | 14.8677 mL | 29.7354 mL | 74.3384 mL |
| 5 mM | 0.5947 mL | 2.9735 mL | 5.9471 mL | 14.8677 mL | |
| 10 mM | 0.2974 mL | 1.4868 mL | 2.9735 mL | 7.4338 mL | |
| 15 mM | 0.1982 mL | 0.9912 mL | 1.9824 mL | 4.9559 mL | |
| 20 mM | 0.1487 mL | 0.7434 mL | 1.4868 mL | 3.7169 mL | |
| 25 mM | 0.1189 mL | 0.5947 mL | 1.1894 mL | 2.9735 mL | |
| 30 mM | 0.0991 mL | 0.4956 mL | 0.9912 mL | 2.4779 mL | |
| 40 mM | 0.0743 mL | 0.3717 mL | 0.7434 mL | 1.8585 mL | |
| 50 mM | 0.0595 mL | 0.2974 mL | 0.5947 mL | 1.4868 mL | |
| 60 mM | 0.0496 mL | 0.2478 mL | 0.4956 mL | 1.2390 mL | |
| 80 mM | 0.0372 mL | 0.1858 mL | 0.3717 mL | 0.9292 mL | |
| 100 mM | 0.0297 mL | 0.1487 mL | 0.2974 mL | 0.7434 mL |
STING agonist-7 Related Classifications
HY-143896 Related Classifications
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