TYT-1
TYT-1 is a sulfonamide-thiourea compound that has inhibitory activity against West Nile virus replication with a 50% effective concentration of 0.7 microM, blocking a post-entry, pre-assembly step of viral replication.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 64803-10-7
- 화학식: C21H17N3O2S3
- 분자량:439.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
>70 μM
Compound: TYT-1
|
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
|
[PMID: 17452483] |
| Vero | CC50 |
>70 μM
Compound: TYT-1
|
Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
|
[PMID: 17452483] |
| Vero | EC50 |
0.7 μM
Compound: TYT-1
|
Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
|
[PMID: 17452483] |
| Vero | EC50 |
7 μM
Compound: TYT-1
|
Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
|
[PMID: 17452483] |
Chemical Information
-
CAS No. 64803-10-7
-
분자량 439.57
-
화학식 C21H17N3O2S3
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SMILES
S=C(N(C1=CC=CC=C1)C2=CC=CC=C2)/N=C(N3C4=CC=CC=C4)\SCS3(=O)=O
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)