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Cat. No.: HY-156524

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USP1-IN-5

USP1-IN-5 (compound 10) is a USP1 inhibitor (IC₅₀<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC₅₀ <50 nM.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2925547-94-8
화학식: C₂₇H₂₃F₃N₈O
분자량:532.52

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

USP1-IN-5 Chemical Structure

CAS No.: 2925547-94-8

사이즈

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

USP1-IN-5 (compound 10) is a USP1 inhibitor (IC₅₀<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC₅₀ <50 nM^[1].

IC₅₀ & Target

IC50: <50 nM (USP1)^[1]

All Deubiquitinase Isoforms :

Chemical Information

CAS No. 2925547-94-8
분자량 532.52
화학식 C₂₇H₂₃F₃N₈O
SMILES

FC(F)(C1=CN(C)C(C23C4C5C2C6C3C4C65CN7N=CC8=C7N=C(C9=C(C%10CC%10)N=CN=C9OC)N=C8)=N1)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu J, et al. Preparation of heteroaromatic compounds as small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof. World Intellectual Property Organization, WO2023083285 A1. 2023-05-19.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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