Vin-F03
Vin-F03 is a potent pancreatic β-cells protective agent with an EC50 of 0.27 μM. Vin-F03 effectively promotes β-cell survival and protects β-cells from STZ (HY-13753)-induced apoptosis. Vin-F03 can be used for type 2 diabetes mellitus research.
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- CAS No.: 2180917-11-5
- 화학식: C22H29N3
- 분자량:335.49
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
IC50 & Target
EC50: 0.27 µM (pancreatic β-cells)[1]
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| INS1(832/13) | EC50 |
0.27 μM
Compound: Vin-F03
|
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
|
[PMID: 31918073] |
Chemical Information
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CAS No. 2180917-11-5
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분자량 335.49
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화학식 C22H29N3
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SMILES
[H][C@]12C3=C4CCN1CCC[C@]2(C=C(N3C5=CC=CC=C54)CNCC)CC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)