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Cat. No.: HY-119702

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YZ51

YZ51 is a derivative of Osalmid (HY-B2116) with stronger ribonucleotide reductase (RR) inhibitory activity and HBV replication inhibition ability than Osalmid. The IC₅₀ of YZ51 against recombinant RR activity is 0.6 μM, and the IC₅₀ against HepG2.2.15 cell RR activity is 23.7 μM.

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CAS No.: 1835652-66-8
화학식: C₁₆H₁₄FNO₂
분자량:271.29

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

YZ51 Chemical Structure

CAS No.: 1835652-66-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 1835652-66-8
분자량 271.29
화학식 C₁₆H₁₄FNO₂
SMILES

O=C(C1=CC=C(C=C1F)C2CC2)NC3=CC=C(C=C3)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xia Liu, et al. "Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 protein." Biochemical Pharmacology 103 (2016): 118-128. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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