Kv3.1 activator-1
Kv3.1 activator-1 is a Kv3.1 voltage-gated potassium channel activator. Kv3.1 activator-1 exhibits distinct activating efficacy in both thallium flux assays and automated patch-clamp electrophysiological assays .
For research use only. We do not sell to patients.
- Formula: C20H19N5O4S
- Molecular Weight:425.46
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
KCNQ2/Q3 |
Kv3.1 activator-1 (3 nM-30 μM) potently activates human Kv3.1 channels in T-REx-HEK-293 cells with an EC50 of 0.047 μM and a maximal activation of 134.9% relative to 15 μM compound 5[1].
Kv3.1 activator-1 activates human Kv3.1 channels in T-REx-HEK-293 cells in an automated patch-clamp assay with an EC50 of 0.16 μM and a maximal activation of 527% relative to TEAC-blocked current baseline[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 425.46
-
Formula C20H19N5O4S
-
SMILES
COC1=CC=C(S(N2N=C(C(NCC3=CN4C(C=CC=C4)=N3)=O)C=C2)(=O)=O)C(C)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Kv3.1 activator-1 Related Classifications
HY-184663 Related Classifications
Powered by Bioz