Kv3.1 activator-2
Kv3.1 activator-2 is a Kv3.1 voltage-gated potassium channel (potassium channel) activator with concentration-dependent activity. Kv3.1 activator-2 opens Kv3.1 potassium channels, increases channel current amplitude, and exerts a positive channel activation effect. Kv3.1 activator-2 can be used in the research of neurological diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C20H17N5O4S
- Peso molecular:423.45
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Kv3.1 activator-2 (compound 10j) activates HEK-293 T-REx cells expressing Kv3.1, with an EC50 of 0.13 μM in Tl+ flux assays[1].
Kv3.1 activator-2 activates HEK-293 T-REx cells expressing Kv3.1, with an EC50 of 0.050 μM and a maximum activation rate of 184% in automated patch-clamp electrophysiological experiments[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 423.45
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Fòrmula C20H17N5O4S
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SMILES
O=C(C1=NN(C=C1)S(=O)(C2=CC3=C(OCC3)C=C2)=O)NCC4=CN5C=CC=CC5=N4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)