Kv3.1 activator-2
Kv3.1 activator-2 is a Kv3.1 voltage-gated potassium channel (potassium channel) activator with concentration-dependent activity. Kv3.1 activator-2 opens Kv3.1 potassium channels, increases channel current amplitude, and exerts a positive channel activation effect. Kv3.1 activator-2 can be used in the research of neurological diseases.
For research use only. We do not sell to patients.
- Formula: C20H17N5O4S
- Molecular Weight:423.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Kv3.1 activator-2 (compound 10j) activates HEK-293 T-REx cells expressing Kv3.1, with an EC50 of 0.13 μM in Tl+ flux assays[1].
Kv3.1 activator-2 activates HEK-293 T-REx cells expressing Kv3.1, with an EC50 of 0.050 μM and a maximum activation rate of 184% in automated patch-clamp electrophysiological experiments[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 423.45
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Formula C20H17N5O4S
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SMILES
O=C(C1=NN(C=C1)S(=O)(C2=CC3=C(OCC3)C=C2)=O)NCC4=CN5C=CC=CC5=N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)