Leukotriene C4 methyl ester
Leukotriene C4 methyl ester is a methyl ester of leukotriene C4. Leukotriene C4 methyl ester can be used for the research of psoriasis.
For research use only. We do not sell to patients.
- CAS No.: 73958-10-8
- Formula: C31H49N3O9S
- Molecular Weight:639.80
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
-
HY-113446
Leukotriene C4Endogenous Metabolite -
HY-131670
(±)9,10-DiHOME9,10-DiHOME Racemate -
HY-113465S
Leukotriene E4-d5Stable Isotope -
HY-B0809S
Theophylline-d6Stable Isotope -
HY-138688
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate12/15-Lipoxygenases Inhibitor -
HY-113484
Leukotriene B5 -
HY-134092
N-Methyl Leukotriene C4CysLT2 Receptor Agonist -
HY-128171
DiflapolinFLAP/sEH Inhibitor -
HY-122124
CAY10583BLT2 Agonist -
HY-113460
11-trans-Leukotriene C4 -
HY-17492
ZafirlukastLeukotriene Receptor Antagonist -
HY-13315A
MontelukastCysLT1 Antagonist
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
Chemical Information
-
CAS No. 73958-10-8
-
Molecular Weight 639.80
-
Formula C31H49N3O9S
-
SMILES
OC([C@@H](N)CCC(N[C@@H](CS[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(OC)=O)C(NCC(O)=O)=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Imiquimod-Induced Psoriasiform Dermatitis
Imiquimod (IMQ)-induced psoriasiform dermatitis is a widely used murine model in which topical application of IMQ, a Toll-like receptor 7 (TLR7) agonist, triggers innate immune activation in the skin and induces a psoriasis-like inflammatory cascade characterized by epidermal hyperplasia, immune cell infiltration, and cytokine production dominated by the IL-23/IL-17 axis. This inflammatory response is mediated through activation of dendritic cells and downstream induction of IL-23, IL-17A, IL-22, and related pro-inflammatory mediators, recapitulating key features of human plaque psoriasis and enabling mechanistic and therapeutic studies. The model is commonly induced using Aldara (5% IMQ cream) applied topically to murine skin, resulting in rapid onset of erythema, scaling, and thickening that can be quantified as disease severity indices and validated histologically.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Leukotriene C4 methyl ester Related Classifications
HY-126716 Related Classifications
Powered by Bioz