Lipid AX4
Based on 1 Customer Validation
Lipid AX4 is an ionizable cationic lipid that can be used to construct lipid nanoparticles (LNPs) for in vivo delivery of nucleic acids (e.g., mRNA, circRNA).
For research use only. We do not sell to patients.
- Purity : 98.5%
- CAS No.: 2735814-23-8
- Formula: C83H155N3O16
- Molecular Weight:1451.13
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Storage:
Solution, -20°C, 2 years
Biological Activity
Description
In Vitro
Lipid AX4 encapsulates circular mRNA (cmRNA) encoding the RBD trimer of the SARS-CoV-2 Delta variant to form the Delta variant circular mRNA vaccine cmRNA-1130[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2735814-23-8
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Appearance Liquid
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Molecular Weight 1451.13
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Formula C83H155N3O16
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Color Colorless to light yellow
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SMILES
O=C(CCN(CCCN(CCCN(CCC(OCCCCOC(C(CCCCCC)CCCC)=O)=O)CCC(OCCCCOC(C(CCCCCC)CCCC)=O)=O)C)CCC(OCCCCOC(C(CCCCCC)CCCC)=O)=O)OCCCCOC(C(CCCCCC)CCCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Protocols
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RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)