Isotope-Labeled Octadecanoids

Linoleic Acid-d₄ is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .

α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.

13(S)-HODE-d₄ is the deuterium labeled 13(S)-HODE.

9(S)-HODE-¹³C₁₈ ((+)-α-Dimophecolic acid-¹³C₁₈) is ¹³C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO.

Cis-Jasmone-d₂ is deuterated labeled Cis-Jasmone (HY-N7058). Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies.

13-Oxo-ODE-d₃ is deuterated labeled 13-Oxo-ODE (HY-131376) 13-Oxo-ODE is an octadecadienoic acid, that can be isolated from the leaves of Artemisia argyi.

9-Nitrooleate-d₁₇ is the deuterium labeled 9-Nitrooleate.

12-Hydroxystearic acid-d₅ is the deuterium labeled 12-Hydroxystearic acid.

Dinor-12-oxo phytodienoic acid-d₅ is the deuterium labeled Dinor-12-oxo phytodienoic acid.

9-OxoODE-d₃ is the deuterium labeled 9-OxoODE.

(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d₅ (10-Hydoxy-cis-12-Octadeceoic Acid-d₅) is deuterium labeled (±)-10-Hydroxy-12(Z)-Octadecenoic acid.

Sebaleic acid-d₁₉ is the deuterium labeled Sebaleic acid (HY-W746683).