Isotope-Labeled Secosteroids

Vitamin D3-¹³C₅ is the ¹³C-labeled Vitamin D3 (HY-15398). Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

5β,6β-Epoxycholestanol-d₇ is deuterium labeled 5β,6β-Epoxycholestanol.

Cholesteryl oleate-d₇-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing.

24(R/S),25-Epoxycholesterol-d₆ is deuterium labeled 24(R/S),25-Epoxycholesterol.

Oxidized 18:2 cholesterol-d₇ is deuterium labeled Oxidized 18:2 cholesterol.

22(R)-Hydroxycholesterol-d₇ (Narthesterol-d₇) is the deuterated-labeled 22(R)-Hydroxycholesterol (HY-116969). 22 (R)-Hydroxycholesterol (Narthesterol) is a natural oxysterol, acting as a LXRα agonist that inhibits cancer cell proliferation. 22 (R)-Hydroxycholesterol activates LXRα-mediated upregulation of downstream ABCA1 expression, enhances apolipoprotein-dependent cholesterol efflux, reduces intracellular cholesterol content, and decreases the production of β-amyloid peptide. 22 (R)-Hydroxycholesterol induces the differentiation of human mesenchymal stem cells into functional dopaminergic neurons. 22 (R)-Hydroxycholesterol is applicable to research related to cancer, Alzheimer's disease, and Parkinson's disease.

Ercalcidiol-d₉ (25-Hydroxy Vitamin D2-d₉) is the deuterium labeled Ercalcidiol (HY-32349). Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.

Ercalcidiol-¹³C₃ (25-Hydroxy Vitamin D2-¹³C3) is the ¹³C-labeled Ercalcidiol (HY-32349). Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.

Calcitriol-d₉ (1,25-Dihydroxyvitamin D3-d₉) is the deuterium labeled Calcitriol (HY-10002). Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

24R-Calcipotriol-d₄ (PRI 2202-d₄; Impurity D of Calcipotriol-d₄) is the deuterium labeled 24R-Calcipotriol. 24R-Calcipotriol is an impurity of Calcipotriol. Calcipotriol is a ligand of VDR-like receptors.

3-epi-25-Hydroxy Vitamin D3-d₆ is the deuterium labeled 3-epi-25-Hydroxy Vitamin D3 (HY-142140). 3-epi-25-Hydroxy Vitamin D3 is the vitamin D metabolite, while vitamin D metabolism highly dependent on macrophage polarization. The C3-epimerase pathway for vitamin D is active in macrophages.

1α,25-Dihydroxyvitamin D3-(23,24,25,26,27-¹³C₅) solution is the ¹³C labeled 1α,25-Dihydroxyvitamin D3.

25-Hydroxyvitamin D2-(20,21,22,26,27-¹³C₅) solution is the ¹³C labeled 25-Hydroxyvitamin D2.

Calcitriol-d₃ is the deuterium labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

Ercalcitriol-¹³C,d₃ is the ¹³C- and deuterium labeled Ercalcitriol. Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.

Alfacalcidol-d₇ is the deuterium labeled Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis.

Vitamin D4-d₅ is the deuterium labeled Vitamin D4. Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol.

Vitamin D3-¹³C₃ is the ¹³C-labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

Calcifediol-¹³C₅ monohydrate is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels.

Calcipotriol-d₄ (MC 903-d₄) is the deuterium labeled Calcipotriol (HY-10001). Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.