Oxo Fatty Acids

2,3-Dinor-6-keto-prostaglandin F1α (2,3-Dinor-6-keto-PGF1α) is the major urinary metabolite of Prostaglandin I₂ (HY-A0126A). 2,3-Dinor-6-keto-prostaglandin F1α is applicable to the research of coronary heart disease.

OPC-8:0 is a nucleoside metabolite.

5-Oxopentanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

Dichloro(1,2-diaminocyclohexane)platinum(II) is a platinum (II) analog and the oxaliplatin parent complex. Dichloro(1,2-diaminocyclohexane)platinum(II) is a potent chemotherapeutic with a wide spectrum of anticancer activity, low toxicity, and lack of cross resistance in many cisplatin-resistant cancers.

Traumatin (12-Oxo-10(E)-dodecenoic acid) is an ester product.

2-Oxooctadecanoic acid is an ester product.

9-Hydroxy-10-oxo-12(Z)-octadecenoic acid ((Z)-9-Hydroxy-10-oxooctadec-12-enoic acid) is an ester product.

10-Oxo-11(E)-octadecenoic acid is an ester product.

12-Oxo-octadecanoic acid (12-Oxo stearic acid) is an ester product.

Suberaldehydic acid (8-Oxooctanoic acid) is an ester product.

12-Oxo-9(Z)-octadecenoic acid is an ester product.

4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of Docosahexaenoic acid (HY-B2167) with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC₅₀ values of approximately 8-16 μM.

7-epi Jasmonic acid is the isomer of (±)-Jasmonic acid (HY-122464). (±)-Jasmonic acid is a plant growth regulator and a derivative of α-linolenic acid. (±)-Jasmonic acid decreases chlorophyll levels in green and etiolated barley leaf segments and inhibits elongation of rice seedlings.

13,14-Dihydro-15-keto-tetranor prostaglandin D2 (Compound VI) is a prostaglandin D2 metabolite. 13,14-Dihydro-15-keto-tetranor prostaglandin D2 as a biomarker can be used to study prostaglandin D2-related diseases.

NLRP3-IN-27 (compound 1) is an inhibitor of NLRP3 with an IC₅₀ value of 0.74 μM. NLRP3 reduces inflammasome-induced pyroptosis in J774A.1 cells. NLRP3-IN-27 can be isolated from Callicarpa arborea Rox.