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Cat. No.: HY-188077

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LSD1-IN-50

LSD1-IN-50 is a lysine-specific histone demethylase 1 (LSD1) inhibitor. LSD1-IN-50 inhibits the proliferation of Kasumi-1 leukemia cells and shows binding affinity to LSD-1. LSD1-IN-50 can be used for the study of cancer, particularly leukemia.

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CAS No.: 1340824-39-6
Formule: C₂₃H₂₂N₆O
Masse moléculaire:398.46

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Please store the product under the recommended conditions in the Certificate of Analysis.

LSD1-IN-50 Chemical Structure

CAS No.: 1340824-39-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Description

Voir tous les produits spécifiques à Isoform Histone Demethylase :

In Vitro

LSD1-IN-50 (compound L02) (25 μM) shows LSD-1 enzymatic inhibition with an inhibition rate of 40.49%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1340824-39-6
Masse moléculaire 398.46
Formule C₂₃H₂₂N₆O
SMILES

N#CC1=CC=C(C2=NC(C3=CC(N=CN4CCN5CCCCC5)=C4C=C3)=NO2)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Wang S, et al. Discovery of a Potent Lysine-Specific Histone Demethylase-1 (LSD-1) Inhibitor for Cancer Treatment via Machine Learning, Molecular Modeling, and In Vitro Validation. Chemistry (Weinheim an der Bergstrasse, Germany). 2025 Dec 01;31(67):e01379. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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- In Vitro
Chemical Information
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Références

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LSD1-IN-50

Voir tous les produits spécifiques à Isoform Histone Demethylase