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Cat. No.: HY-117447

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LY303336

LY303336 is an antagonist of polysubstituted 4-aminoimidazole AT1 receptor with an IC₅₀ value of 5.2 nM.

For research use only. We do not sell to patients.

CAS No.: 157187-00-3
Formula: C₃₀H₃₇N₄O₁₁PS
Molecular Weight:692.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

LY303336 Chemical Structure

CAS No.: 157187-00-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

LY303336 is an antagonist of polysubstituted 4-aminoimidazole AT1 receptor with an IC₅₀ value of 5.2 nM^[1].

All Angiotensin Receptor Isoforms :

Chemical Information

CAS No. 157187-00-3
Molecular Weight 692.67
Formula C₃₀H₃₇N₄O₁₁PS
SMILES

CCCCCC[C@@H](N1C=C(N=C1)NC(C2=C(C=CC=C2)S(=O)(O)=O)=O)C(N3[C@@H](C[C@@H](C3)OC4=CC=C(C=C4)CP(O)(O)=O)C(O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. P M Vanderheyden, et al. Inhibition of angiotensin II-induced inositol phosphate production by triacid nonpeptide antagonists in CHO cells expressing human AT1 receptors. Pharm Res. 2000 Dec;17(12):1482-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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LY303336

All Angiotensin Receptor Isoforms