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  4. Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic

Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic is a biochemical assay reagent that can be used for synthesis of Ac-macropa (HY-163608). Ac-macropa is a PSMA-targeted Actinium-225 Conjugate, and can be used for study of prostate cancer.

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Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic

Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic Estructura química

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Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic Related Antibodies

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Descripciòn

Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic is a biochemical assay reagent that can be used for synthesis of Ac-macropa (HY-163608). Ac-macropa is a PSMA-targeted Actinium-225 Conjugate, and can be used for study of prostate cancer[1][2].

In Vitro

Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic can be labled with Actinium-225 to synthesis PSMA-Targeted Actinium-225 Conjugate[1].
PSMA-Targeted Actinium-225 Conjugate exhibits potent, dose-dependent cytotoxicity in PSMA-expressing C4-2, LNCaP, MDA-PCa-2b, and 22Rv1 prostate cancer cells, but not in PSMA-negative PC-3 and DU-145 prostate cancer cells[1].
PSMA-Targeted Actinium-225 Conjugate induces G2/M cell cycle arrest, dose-dependent reactive oxygen species formation, and DNA damage in PSMA-expressing C4-2, LNCaP, and 22Rv1 prostate cancer cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic Related Antibodies
Peso molecular

782.95

Fòrmula

C39H54N6O9S
SMILES

S=C(NC1=CC=C(CCOC2=CC(C([OH])=O)=[N]C(C[N]3CC[O]CC[O]CC[N](CC[O]CC[O]CC3)CC4=CC=CC(C([OH])=O)=[N]4)=C2)C=C1)NCCCC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic Related Classifications

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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinicBiochemical Assay ReagentsPC-3DU-145LNCaPactinium-225darolutamidePSMAMDA-PCa-2bC4-222Rv1prostate cancerInhibitorinhibitorinhibit

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Nombre del producto:
Macropa-4-(4-(3-butylthioureido)phenethoxy)picolinic
Cat. No.:
HY-186220
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