Martinostat hydrochloride
Based on 1 Customer Validation
Martinostat hydrochloride is a HDAC inhibitor and can be labeled with radionuclides for quantitative imaging of HDACs in vivo in the central nervous system and major peripheral organs.
For research use only. We do not sell to patients.
- Purity: 99.01%
- Formula: C22H31ClN2O2
- Molecular Weight:390.95
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 390.95
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Formula C22H31ClN2O2
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Color Off-white to pink
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SMILES
CN(CC(C=C1)=CC=C1/C=C/C(NO)=O)CC2(C[C@@H](C3)C4)C[C@@H]4C[C@@H]3C2.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (319.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Changning Wang, et al. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs. J Med Chem. 2014 Oct 9;57(19):7999-8009. [Content Brief]
[2]. Tharick A Pascoal, et al. [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease. Nat Commun. 2022 Jul 19;13(1):4171. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5579 mL | 12.7894 mL | 25.5787 mL | 63.9468 mL |
| 5 mM | 0.5116 mL | 2.5579 mL | 5.1157 mL | 12.7894 mL | |
| 10 mM | 0.2558 mL | 1.2789 mL | 2.5579 mL | 6.3947 mL | |
| 15 mM | 0.1705 mL | 0.8526 mL | 1.7052 mL | 4.2631 mL | |
| 20 mM | 0.1279 mL | 0.6395 mL | 1.2789 mL | 3.1973 mL | |
| 25 mM | 0.1023 mL | 0.5116 mL | 1.0231 mL | 2.5579 mL | |
| 30 mM | 0.0853 mL | 0.4263 mL | 0.8526 mL | 2.1316 mL | |
| 40 mM | 0.0639 mL | 0.3197 mL | 0.6395 mL | 1.5987 mL | |
| 50 mM | 0.0512 mL | 0.2558 mL | 0.5116 mL | 1.2789 mL | |
| 60 mM | 0.0426 mL | 0.2132 mL | 0.4263 mL | 1.0658 mL | |
| 80 mM | 0.0320 mL | 0.1599 mL | 0.3197 mL | 0.7993 mL | |
| 100 mM | 0.0256 mL | 0.1279 mL | 0.2558 mL | 0.6395 mL |
Martinostat hydrochloride Related Classifications
HY-160092A Related Classifications
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