1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Mastoparan X

Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells.

For research use only. We do not sell to patients.

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Mastoparan X Chemical Structure

Mastoparan X Chemical Structure

CAS No. : 72093-22-2

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Based on 1 publication(s) in Google Scholar

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Description

Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells[1].

IC50 & Target

GTP-binding regulatory protein (G protein)[1]

In Vitro

Mastoparan X (1.5 mM) interacts with phospholipid bicelles, and results the line broadening[2].
Mastoparan X binds to the membrane, and increases the cell’s permeability to cations leading to a disruption in the electrolyte balance and cell lysis[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1555.97

Formula

C73H126N20O15S

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

INWKGIAAMAKKLL-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (64.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6427 mL 3.2134 mL 6.4269 mL
5 mM 0.1285 mL 0.6427 mL 1.2854 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6427 mL 3.2134 mL 6.4269 mL 16.0671 mL
5 mM 0.1285 mL 0.6427 mL 1.2854 mL 3.2134 mL
10 mM 0.0643 mL 0.3213 mL 0.6427 mL 1.6067 mL
15 mM 0.0428 mL 0.2142 mL 0.4285 mL 1.0711 mL
20 mM 0.0321 mL 0.1607 mL 0.3213 mL 0.8034 mL
25 mM 0.0257 mL 0.1285 mL 0.2571 mL 0.6427 mL
30 mM 0.0214 mL 0.1071 mL 0.2142 mL 0.5356 mL
40 mM 0.0161 mL 0.0803 mL 0.1607 mL 0.4017 mL
50 mM 0.0129 mL 0.0643 mL 0.1285 mL 0.3213 mL
60 mM 0.0107 mL 0.0536 mL 0.1071 mL 0.2678 mL
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Mastoparan X Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mastoparan X
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HY-P2705
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