Methyl carbazole-3-carboxylate
Based on 1 Customer Validation
Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels.
For research use only. We do not sell to patients.
- Purity: 98.10%
- CAS No.: 97931-41-4
- Formula: C14H11NO2
- Molecular Weight:225.24
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
36.9 μM
Compound: 5
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Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay
Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay
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[PMID: 22093759] |
| KB | IC50 |
59.7 μM
Compound: 18
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Cytotoxicity against human KB cells by resazurin reduction assay
Cytotoxicity against human KB cells by resazurin reduction assay
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[PMID: 22482432] |
| MCF7 | IC50 |
169.8 μM
Compound: 18
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Cytotoxicity against human MCF7 cells by resazurin reduction assay
Cytotoxicity against human MCF7 cells by resazurin reduction assay
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[PMID: 22482432] |
| NCI-H187 | IC50 |
95.8 μM
Compound: 18
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Cytotoxicity against human NCI-H187 cells by resazurin reduction assay
Cytotoxicity against human NCI-H187 cells by resazurin reduction assay
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[PMID: 22482432] |
| Neutrophil | IC50 |
>10 μM
Compound: 20
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Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins
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[PMID: 24798144] |
| Neutrophil | IC50 |
4.3 μM
Compound: 20
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Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry
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[PMID: 24798144] |
Chemical Information
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CAS No. 97931-41-4
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Appearance Solid
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Molecular Weight 225.24
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Formula C14H11NO2
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Color Light brown to brown
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SMILES
COC(C1=CC2=C(C=C1)NC3=CC=CC=C23)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 125 mg/mL (554.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4397 mL | 22.1985 mL | 44.3971 mL | 110.9927 mL |
| 5 mM | 0.8879 mL | 4.4397 mL | 8.8794 mL | 22.1985 mL | |
| 10 mM | 0.4440 mL | 2.2199 mL | 4.4397 mL | 11.0993 mL | |
| 15 mM | 0.2960 mL | 1.4799 mL | 2.9598 mL | 7.3995 mL | |
| 20 mM | 0.2220 mL | 1.1099 mL | 2.2199 mL | 5.5496 mL | |
| 25 mM | 0.1776 mL | 0.8879 mL | 1.7759 mL | 4.4397 mL | |
| 30 mM | 0.1480 mL | 0.7400 mL | 1.4799 mL | 3.6998 mL | |
| 40 mM | 0.1110 mL | 0.5550 mL | 1.1099 mL | 2.7748 mL | |
| 50 mM | 0.0888 mL | 0.4440 mL | 0.8879 mL | 2.2199 mL | |
| 60 mM | 0.0740 mL | 0.3700 mL | 0.7400 mL | 1.8499 mL | |
| 80 mM | 0.0555 mL | 0.2775 mL | 0.5550 mL | 1.3874 mL | |
| 100 mM | 0.0444 mL | 0.2220 mL | 0.4440 mL | 1.1099 mL |
Methyl carbazole-3-carboxylate Related Classifications
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