Methyl carbazole-3-carboxylate

Cat. No.: HY-N3288 Purity: 98.10%: Data Sheet
COA

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Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Methyl carbazole-3-carboxylate 화학구조

CAS No. : 97931-41-4

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Methylcarbazole-3-carboxylate is a carbazole alkaloid can be isolated from the peel of Clausena lansium (Lour.) Skeels^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	36.9 μM Compound: 5	Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay Growth inhibition of human HepG2 cells after 48 hrs by WST-8 based CCK8 assay	[PMID: 22093759]
KB	IC₅₀	59.7 μM Compound: 18	Cytotoxicity against human KB cells by resazurin reduction assay Cytotoxicity against human KB cells by resazurin reduction assay	[PMID: 22482432]
MCF7	IC₅₀	169.8 μM Compound: 18	Cytotoxicity against human MCF7 cells by resazurin reduction assay Cytotoxicity against human MCF7 cells by resazurin reduction assay	[PMID: 22482432]
NCI-H187	IC₅₀	95.8 μM Compound: 18	Cytotoxicity against human NCI-H187 cells by resazurin reduction assay Cytotoxicity against human NCI-H187 cells by resazurin reduction assay	[PMID: 22482432]
Neutrophil	IC₅₀	>10 μM Compound: 20	Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced elastase release for 5 mins	[PMID: 24798144]
Neutrophil	IC₅₀	4.3 μM Compound: 20	Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry Antiinflammatory activity in human neutrophil assessed as inhibition of FMLP/CB-induced superoxide anion generation pretreated for 5 mins by spectrophotometry	[PMID: 24798144]

분자량

225.24

화학식

C₁₄H₁₁NO₂

CAS No.

97931-41-4

Appearance

Solid

Color

Light brown to brown

SMILES

COC(C1=CC2=C(C=C1)NC3=CC=CC=C23)=O

Structure Classification

Alkaloids

Initial Source

선적

Room temperature in continental US; may vary elsewhere.

보관

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

용액&용해도

In Vitro:

DMSO : 125 mg/mL (554.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.4397 mL	22.1985 mL	44.3971 mL
5 mM	0.8879 mL	4.4397 mL	8.8794 mL
10 mM	0.4440 mL	2.2199 mL	4.4397 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.10%

Select Batch:

Data Sheet (267 KB) SDS (393 KB)

COA (246 KB) HNMR (240 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Deng HD, et al. Carbazole alkaloids from the peels of Clausena lansium. J Asian Nat Prod Res. 2014 Oct;16(10):1024-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.4397 mL	22.1985 mL	44.3971 mL	110.9927 mL
	5 mM	0.8879 mL	4.4397 mL	8.8794 mL	22.1985 mL
	10 mM	0.4440 mL	2.2199 mL	4.4397 mL	11.0993 mL
	15 mM	0.2960 mL	1.4799 mL	2.9598 mL	7.3995 mL
	20 mM	0.2220 mL	1.1099 mL	2.2199 mL	5.5496 mL
	25 mM	0.1776 mL	0.8879 mL	1.7759 mL	4.4397 mL
	30 mM	0.1480 mL	0.7400 mL	1.4799 mL	3.6998 mL
	40 mM	0.1110 mL	0.5550 mL	1.1099 mL	2.7748 mL
	50 mM	0.0888 mL	0.4440 mL	0.8879 mL	2.2199 mL
	60 mM	0.0740 mL	0.3700 mL	0.7400 mL	1.8499 mL
	80 mM	0.0555 mL	0.2775 mL	0.5550 mL	1.3874 mL
	100 mM	0.0444 mL	0.2220 mL	0.4440 mL	1.1099 mL