MK-1832
MK-1832 (Compound 32) is a selective Kv1.5 inhibitor (IC50 = 86 nM). MK-1832 is a P-glycoprotein substrate. MK-1832 can be used in atrial fibrillation research.
For research use only. We do not sell to patients.
- CAS No.: 935868-50-1
- Formula: C23H17Cl2N3O
- Molecular Weight:422.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30000 nM
Compound: 2; MK-1832; ent-32
|
Displacement of [3H]-MK499 from human ERG IKr channel expressed in HEK293 cell membranes
Displacement of [3H]-MK499 from human ERG IKr channel expressed in HEK293 cell membranes
|
[PMID: 28131713] |
Chemical Information
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CAS No. 935868-50-1
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Molecular Weight 422.31
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Formula C23H17Cl2N3O
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SMILES
O[C@@H](C1=CC=CN=C1C2=CC(Cl)=CC(Cl)=C2)C(C3=CC=CN=C3)C4=CC=CN=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)