2. Moricizine Hydrochloride

Moricizine Hydrochloride  (Synonyms: EN 313; Ethmozin; Moracizine)

Cat. No.: HY-B0615A Purity: ≥98.0%
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Moricizine Hydrochloride (EN 313) is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period.

For research use only. We do not sell to patients.

Moricizine Hydrochloride Chemical Structure

Moricizine Hydrochloride Chemical Structure

CAS No. : 29560-58-5

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1 mg USD 43 In-stock
5 mg USD 101 In-stock
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Other Forms of Moricizine Hydrochloride:

Moricizine Hydrochloride Related Antibodies

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Description

Moricizine Hydrochloride (EN 313) is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period[1].

Clinical Trial
Molecular Weight

463.98

Formula

C22H26ClN3O4S
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(OCC)NC(C=C1N2C(CCN3CCOCC3)=O)=CC=C1SC4=C2C=CC=C4.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (215.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1553 mL 10.7763 mL 21.5527 mL
5 mM 0.4311 mL 2.1553 mL 4.3105 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1553 mL 10.7763 mL 21.5527 mL 53.8816 mL
5 mM 0.4311 mL 2.1553 mL 4.3105 mL 10.7763 mL
10 mM 0.2155 mL 1.0776 mL 2.1553 mL 5.3882 mL
15 mM 0.1437 mL 0.7184 mL 1.4368 mL 3.5921 mL
20 mM 0.1078 mL 0.5388 mL 1.0776 mL 2.6941 mL
25 mM 0.0862 mL 0.4311 mL 0.8621 mL 2.1553 mL
30 mM 0.0718 mL 0.3592 mL 0.7184 mL 1.7961 mL
40 mM 0.0539 mL 0.2694 mL 0.5388 mL 1.3470 mL
50 mM 0.0431 mL 0.2155 mL 0.4311 mL 1.0776 mL
60 mM 0.0359 mL 0.1796 mL 0.3592 mL 0.8980 mL
80 mM 0.0269 mL 0.1347 mL 0.2694 mL 0.6735 mL
100 mM 0.0216 mL 0.1078 mL 0.2155 mL 0.5388 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Moricizine29560-58-5EN 313 Ethmozin MoracizineEN313EN-313Inhibitorinhibitorinhibit

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