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Cat. No.: HY-171237

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mPGES1-IN-9

mPGES1-IN-9 (compound 1_8) is a mPGES1 inhibitor (IC₅₀=0.5 μM), which can be used in anti-inflammatory research.

For research use only. We do not sell to patients.

CAS No.: 556033-92-2
Formula: C₂₅H₁₈N₄OS
Molecular Weight:422.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

mPGES1-IN-9 Chemical Structure

CAS No.: 556033-92-2

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Top Publications Citing

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

mPGES1-IN-9 (compound 1_8) is a mPGES1 inhibitor (IC₅₀=0.5 μM), which can be used in anti-inflammatory research^[1].

Chemical Information

CAS No. 556033-92-2
Molecular Weight 422.50
Formula C₂₅H₁₈N₄OS
SMILES

O=C(CSC1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)N=N1)C4=CNC5=C4C=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. He S, et al. Discovery of highly potent microsomal prostaglandin e2 synthase 1 inhibitors using the active conformation structural model and virtual screen. J Med Chem. 2013 Apr 25;56(8):3296-309. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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