2. Anti-infection
  3. SARS-CoV Virus Protease
  4. MPI3

MPI3 is a reversible covalent SARS-CoV-2 MPro inhibitor with an enzymatic IC50 of 8.5 nM. MPI3 can be used for the research of covid-19.

For research use only. We do not sell to patients.

MPI3

MPI3 Chemical Structure

CAS No. : 890648-84-7

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MPI3 Related Antibodies

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Description

MPI3 is a reversible covalent SARS-CoV-2 MPro inhibitor with an enzymatic IC50 of 8.5 nM. MPI3 can be used for the research of covid-19[1].

In Vitro

MPI3 potently inhibits purified SARS-CoV-2 MPro with an enzymatic IC50 of 0.0085 μM[1].
MPI3 (72 h) shows weak cellular inhibition of SARS-CoV-2 MPro in transiently transfected HEK293T/17 cells, with a cellular IC50 greater than 2 μM[1].
MPI3 weakly inhibits SARS-CoV-2 replication in Vero E6 cells, with an antiviral EC50 greater than 5 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MPI3 Related Antibodies
Molecular Weight

502.60

Formula

C26H38N4O6
CAS No.
SMILES

O=C(NCC1)[C@@H]1C[C@@H](C=O)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MPI3 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MPI3890648-84-7MPI 3MPI-3SARS-CoVVirus ProteaseSARS coronavirusMProcovid-19SARS-CoV-2 main proteaseVero E6 cellsHEK293T/17 cellsInhibitorinhibitorinhibit

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