NH-bis(C1-PEG1-Boc)
Based on 1 Customer Validation
NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 2171072-53-8
- Formula: C17H33NO6
- Molecular Weight:347.45
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2171072-53-8
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Appearance Liquid (Density: 1.043±0.06 g/cm3)
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Molecular Weight 347.45
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Formula C17H33NO6
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Color Colorless to light yellow
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SMILES
NC(COCCC(OC(C)(C)C)=O)COCCC(OC(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (287.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8781 mL | 14.3906 mL | 28.7811 mL | 71.9528 mL |
| 5 mM | 0.5756 mL | 2.8781 mL | 5.7562 mL | 14.3906 mL | |
| 10 mM | 0.2878 mL | 1.4391 mL | 2.8781 mL | 7.1953 mL | |
| 15 mM | 0.1919 mL | 0.9594 mL | 1.9187 mL | 4.7969 mL | |
| 20 mM | 0.1439 mL | 0.7195 mL | 1.4391 mL | 3.5976 mL | |
| 25 mM | 0.1151 mL | 0.5756 mL | 1.1512 mL | 2.8781 mL | |
| 30 mM | 0.0959 mL | 0.4797 mL | 0.9594 mL | 2.3984 mL | |
| 40 mM | 0.0720 mL | 0.3598 mL | 0.7195 mL | 1.7988 mL | |
| 50 mM | 0.0576 mL | 0.2878 mL | 0.5756 mL | 1.4391 mL | |
| 60 mM | 0.0480 mL | 0.2398 mL | 0.4797 mL | 1.1992 mL | |
| 80 mM | 0.0360 mL | 0.1799 mL | 0.3598 mL | 0.8994 mL | |
| 100 mM | 0.0288 mL | 0.1439 mL | 0.2878 mL | 0.7195 mL |
NH-bis(C1-PEG1-Boc) Related Classifications
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