Apo6619
Apo6619 is an iron chelator with antibacterial activity that inhibits a variety of common bacteria associated with hospital-acquired infections. Apo6619 inhibits the growth of relevant bacterial strains in cation-adjusted Mueller-Hinton broth and RPMI 1640 tissue culture medium. Apo6619 can be used in antibacterial research on hospital-acquired infection-related bacteria based on the iron chelation mechanism.
For research use only. We do not sell to patients.
- CAS No.: 887774-94-9
- Formula: C11H14N2O3
- Molecular Weight:222.24
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Apo6619 inhibits the growth of A. baumannii ATCC 17978 and 19606 in CAMHB, with an MIC of 256 μg/mL for both strains; it also exhibits an MIC of 256 μg/mL against E. coli ATCC 35718 and 43888[1].
Apo6619 exhibits MIC values of > 512 μg/mL against Staphylococcus aureus ATCC 25923, 43300, Pseudomonas aeruginosa PAO1, ATCC 27853, and Klebsiella pneumoniae BAA-2146, 700603 in CAMHB[1].
Apo6619 inhibits the growth of A. baumannii ATCC 17978 and 19606 in RPMI 1640 medium, with MIC values of 64 μg/mL and 128 μg/mL, respectively; it exhibits an MIC of 256 μg/mL against both E. coli ATCC 35718 and 43888[1].
The MIC of Apo6619 against P. aeruginosa PAO1, K. pneumoniae BAA-2146 and 700603 in RPMI 1640 medium is 512 μg/mL, while its MIC against P. aeruginosa ATCC 27853 is > 512 μg/mL[1].
Apo6619 exhibits antibacterial activity in the time-kill assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 887774-94-9
-
Molecular Weight 222.24
-
Formula C11H14N2O3
-
SMILES
O=C1C=C(N(C(C(=O)NC)=C1O)C2CC2)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Apo6619 Related Classifications
HY-165465 Related Classifications
Powered by Bioz
- Apo6619
- 887774-94-9
- Apo 6619
- Apo-6619
- Bacterial
- Escherichia coli
- Pseudomonas aeruginosa
- cation-adjusted Mueller-Hinton broth
- nosocomial bacterial infections
- Acinetobacter baumannii
- Gram-negative bacterial strains
- Staphylococcus aureus
- Klebsiella pneumoniae
- RPMI 1640 tissue culture medium
- Inhibitor
- inhibitor
- inhibit