TLP-3
TLP-3, Temporin L (HY-P2523) analogue, is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 7.0 μM. TLP-3 inhibits protease activity through stabilizing hydrogen bonding and hydrophobic interactions with key enzyme residues. TLP-3 can be used for the research of ARS-CoV‑2 infection.
For research use only. We do not sell to patients.
- Formula: C83H110N20O17
- Molecular Weight:1659.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
TLP-3 stabilizes SARS-CoV-2 Mpro via favorable domain arrangement and forms strong hydrogen bond interactions with critical Mpro residues[1].
TLP-3 inhibits SARS-CoV-2 Mpro with an IC50 of 7.0 ± 1.5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1659.89
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Formula C83H110N20O17
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Sequence
Ser-Ala-Phe-Trp-Gln-Trp-Phe-Ser-Lys-Phe-Leu-Gly-Arg
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Sequence Shortening
SAFWQWFSKFLGR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLP-3 Related Classifications
HY-P11579 Related Classifications
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