[Nle13]-Motilin
[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist.
For research use only. We do not sell to patients.
- CAS No.: 55524-56-6
- Formula: C121H190N34O35
- Molecular Weight:2681.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
[Nle13]-Motilin (0.1-30 nM, 15 min) increases the amplitude of electrically-evoked, neuronally-mediated contractions in the isolated gastric antrum[1].
[Nle13]-Motilin (0.3 μM, 10 min) induces a moderate increase in spontaneous contractility in the stomach[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 55524-56-6
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Molecular Weight 2681.01
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Formula C121H190N34O35
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Sequence Shortening
FVPIFTYGELQR-{Nle}-QEKERNKGQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Dass NB, et al. The rabbit motilin receptor: molecular characterisation and pharmacology. Br J Pharmacol. 2003 Nov;140(5):948-54. [Content Brief]
[2]. Venkova K, et al. Effect of TZP-201, a novel motilin receptor antagonist, in the colon of the musk shrew (Suncus murinus). J Pharm Pharmacol. 2009 Mar;61(3):367-73. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)