1. Immunology/Inflammation
  2. NOD-like Receptor (NLR)
  3. NLRP3-IN-38

NLRP3-IN-38 (Compound 18) is an inhibitor for NOD-like receptor protein 3 (NLRP3), that inhibits NLRP3 inflammasome activation with an EC50 of 23 nM.

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NLRP3-IN-38

NLRP3-IN-38 Estructura química

No. CAS : 3033054-46-2

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Descripciòn

NLRP3-IN-38 (Compound 18) is an inhibitor for NOD-like receptor protein 3 (NLRP3), that inhibits NLRP3 inflammasome activation with an EC50 of 23 nM[1].

IC50 & Target

NLRP3 inflammasome

23 nM (EC50)

Peso molecular

418.41

Fòrmula

C21H21F3N4O2

No. CAS
SMILES

C[C@H]1CN(C[C@H]([C@@H]1O)C)C2=C3C=NC=CC3=C(N=N2)C4=CC=C(C=C4O)C(F)(F)F

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Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
NLRP3-IN-38
Cat. No.:
HY-163497
Cantidad:
MCE Japan Authorized Agent: